The traits of the primary temperament, Melancholy, may be altered or modified in some significant way due to the influence of the secondary temperament.
Also, arsenic was used in a poultice bag to 'draw out' the excess humor s that led to symptoms of the plague.
Who is a melancholic:
It is necessary, therefore, to study it and at the same time to find out how this temperament manifests itself in each individual.
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We also see evidence of people's unconscious mind reverting from unconscious to conscious behaviour when they are under the influence of alcohol or significant stress.
You can find all possible combinations and how they translate to 16 personalities theory on the main temperaments page.